E-ASPIRe

Extension of the Apical Suspension Repair for Vault Prolapse

The E-ASPIRe clinical trial extends the follow-up of women in the ASPIRe clinical trial up to 10 years from the time of surgery. The primary aim for ASPIRe was to find out how the results of the surgical procedures (abdominal sacral colpopexy, native tissue repair, or apical transvaginal mesh repair) compare to each other as well as the advantages and/or disadvantages, risks and benefits, and the effect on quality of life of each surgery when used to repair vaginal vault (apical) prolapse. The ASPIRe cohort represents a unique opportunity to understand the longer-term efficacy and safety outcomes of a native tissue repair, transvaginal mesh, and abdominal sacral colpopexy for post-hysterectomy apical (vault) prolapse. Participants will complete annual study visits either in-person or remotely, and will complete a reduced set of questionnaires (PFDI-20, PFIQ, PGI-I, PISQ-IR, SF-12, DRS-SDS).